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Company ReportsMirum Pharmaceuticals

Mirum Pharmaceuticals(MIRM)

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Marketed Drugs

Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Livmarli	Maralixibat	2021-09-29	2031-2040	Pruritus , Alagille syndrome
Cholbam	Cholic acid	2015-03-17		Zellweger syndrome , Inborn errors metabolism

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

neurofibromatosis 1

,

neurofibromatoses

,

,

hyperlipidemias

,

central nervous system neoplasms

,

,

clostridium infections

,

colonic neoplasms

,

rectal neoplasms

,

,

hyperlipoproteinemia type iv

,

metabolic syndrome

,

hypertriglyceridemia

,

familial combined hyperlipidemia

,

liver function tests

,

,

alcoholic hepatitis

,

parkinson disease

,

huntington disease

,

cardiovascular diseases

,

,

alcoholic fatty liver

,

gastrointestinal diseases

,

digestive system diseases

,

liver neoplasms

,

,

,

rheumatoid arthritis

,

,

biliary tract diseases

,

barrett esophagus

,

,

cystic fibrosis

,

,

muscle spasticity

,

hereditary spastic paraplegia

,

,

irritable bowel syndrome

,

,

cardiomyopathies

,

disease progression

,

,

neoplasm metastasis

,

radiation injuries

,

,

insulin resistance

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

,

,

x-linked genetic diseases

,

smith-lemli-opitz syndrome

,

,

,

,

bile duct diseases

,

adolescent development

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

obstructive jaundice

,

,

esophageal neoplasms

,

head and neck neoplasms

,

end stage liver disease

,

,

,

breast neoplasms

,

,

healthy volunteers/patients

,

intrahepatic cholestasis

,

colorectal neoplasms

,

cerebrotendinous xanthomatosis

,

,

,

,

pregnancy complications

,

glucose intolerance

,

sclerosing cholangitis

,

peroxisomal disorders

,

zellweger syndrome

,

infantile refsum disease

,

adrenoleukodystrophy

,

,

,

adenomatous polyposis coli

,

nasopharyngeal neoplasms

,

,

retinal detachment

,

dissociative disorders

,

chronic hepatitis c

,

duodenal neoplasms

,

inborn errors metabolism

,

inborn errors lipid metabolism

,

inborn errors steroid metabolism

,

,

inborn genetic diseases

,

,

child nutrition disorders

,

ulcerative colitis

,

,

,

,

thyroid diseases

,

,

chronic hepatitis

,

acute cholecystitis

,

,

acalculous cholecystitis

,

,

,

biliary liver cirrhosis

,

,

,

,

liver cirrhosis

,

non-alcoholic fatty liver disease

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

cholecystolithiasis

,

,

,

,

,

chemical and drug induced liver injury

,

,

hyperbilirubinemia

,

gestational diabetes

,

,

autoimmune hepatitis

,

,

,

neonatal hyperbilirubinemia

,

malabsorption syndromes

,

lipid metabolism disorders

,

,

,

hemolytic anemia

,

chronic kidney failure

,

kidney diseases

,

short bowel syndrome

,

cardiac surgical procedures

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

fontan procedure

,

,

communicable diseases

,

,

brain neoplasms

,

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors

,

,

retinal neoplasms

,

neuroectodermal tumors

,

phenylketonurias

,

appetite regulation

,

,

liver transplantation

,

reperfusion injury

,

gastroesophageal reflux

,

,

biliary atresia

,

liver regeneration

,

,

hepatocellular carcinoma

,

cholangiocarcinoma

,

wounds and injuries

,

cerebrotendinous xanthomatosis

,

,

healthy volunteers/patients

,

alagille syndrome

,

,

biliary liver cirrhosis

,

substance withdrawal syndrome

,

biliary atresia

,

sclerosing cholangitis

,

,

,

intrahepatic cholestasis

,

Maralixibat chloride

,

healthy volunteers/patients

,

alagille syndrome

,

,

biliary liver cirrhosis

,

substance withdrawal syndrome

,

biliary atresia

,

sclerosing cholangitis

,

,

,

intrahepatic cholestasis

,

anxiety disorders

,

healthy volunteers/patients

,

huntington disease

,

non-alcoholic fatty liver disease

,

,

,

,

,

breast neoplasms

,

,

chronic hepatitis b

,

chronic hepatitis

,

parkinson disease

,

eosinophilic esophagitis

,

,

biliary liver cirrhosis

,

,

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

diffuse scleroderma

,

,

,

,

short bowel syndrome

,

myocardial infarction

,

drug resistance

,

heat stress disorders

,

,

combat disorders

,

traumatic stress disorders

,

gastrointestinal diseases

,

,

intestinal diseases

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

depressive disorder

,

,

,

major depressive disorder

,

,

,

,

kidney diseases

,

,

cardiovascular diseases

,

chronic renal insufficiency

,

chronic hepatitis c

,

papillomavirus infections

,

,

,

pulmonary embolism

,

,

thromboembolism

,

,

venous thrombosis

,

,

papillomavirus vaccines

,

,

meningococcal infections

,

,

glucose metabolism disorders

,

metabolic diseases

,

vascular diseases

,

,

metabolic syndrome

,

endocrine system diseases

,

hypertriglyceridemia

,

rheumatoid arthritis

,

atrial fibrillation

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

systemic scleroderma

,

juvenile arthritis

,

behcet syndrome

,

dermatomyositis

,

ankylosing spondylitis

,

sjogren's syndrome

,

systemic lupus erythematosus

,

,

spondylarthritis

,

systemic vasculitis

,

diabetic neuropathies

,

hypercholesterolemia

,

,

facial nerve diseases

,

,

wasting syndrome

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

systemic scleroderma

,

diffuse scleroderma

,

,

ovarian neoplasms

,

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

liver neoplasms

,

nervous system neoplasms

,

non-hodgkin lymphoma

,

b-cell lymphoma

,

,

hodgkin disease

,

,

,

prostatic neoplasms

,

,

testicular neoplasms

,

reactive arthritis

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

hematologic neoplasms

,

graft vs host disease

,

myeloproliferative disorders

,

hematologic diseases

,

aplastic anemia

,

,

male breast neoplasms

,

,

,

triple negative breast neoplasms

,

,

invasive hydatidiform mole

,

,

breast neoplasms

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

large b-cell lymphoma diffuse

,

inflammatory breast neoplasms

,

,

,

lymphoid leukemia

,

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

brain stem neoplasms

,

,

,

,

,

small cell lung carcinoma

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

,

pregnancy complications

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

,

digestive system diseases

,

healthy volunteers/patients

,

alzheimer disease

,

female genital neoplasms

,

,

chronic hepatitis b

,

,

major depressive disorder

,

depressive disorder

,

triple negative breast neoplasms

,

pancreatic neoplasms

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

sickle cell anemia

,

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

parkinson disease

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

chronic hepatitis

,

rectal neoplasms

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

,

neoplasm metastasis

,

antiphospholipid syndrome

,

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

lupus nephritis

,

human influenza

,

breast neoplasms

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

myeloid leukemia acute

,

multiple sclerosis

,

,

,

hepatocellular carcinoma

,

colonic neoplasms

,

thrombocytopenic purpura idiopathic

,

liver cirrhosis

,

neuromyelitis optica

,

membranous glomerulonephritis

,

chronic progressive multiple sclerosis

,

,

nephrotic syndrome

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

hemolytic anemia autoimmune

,

,

chronic hepatitis c

,

,

,

rheumatoid arthritis

,

,

,

juvenile arthritis

,

,

follicular lymphoma

,

,

,

myelodysplastic syndromes

,

,

,

acquired immunodeficiency syndrome

,

kidney transplantation

,

drug-related side effects and adverse reactions

,

heart disease risk factors

,

cognitive dysfunction

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

,

pregnancy complications

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

,

digestive system diseases

,

Histone-arginine methyltransferase carm1

,

respiratory aspiration

,

thrombocytopenic purpura idiopathic

,

,

photosensitivity disorders

,

renal cell carcinoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

healthy volunteers/patients

,

rheumatoid arthritis

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

,

respiratory tract infections

,

,

tendon injuries

,

anxiety disorders

,

,

,

,

,

,

,

,

chronic hepatitis c

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

acquired immunodeficiency syndrome

,

,

inflammatory breast neoplasms

,

atrial fibrillation

,

,

macular degeneration

,

depressive disorder

,

ovarian neoplasms

,

endometrial neoplasms

,

ovarian epithelial carcinoma

,

immunologic deficiency syndromes

,

,

pulmonary tuberculosis

,

,

thrombocytopenia

,

non-small-cell lung carcinoma

,

,

non-hodgkin lymphoma

,

systemic lupus erythematosus

,

,

major depressive disorder

,

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

,

,

respiratory syncytial viruses

,

,

allergic rhinitis

,

allergic rhinitis perennial

,

breast neoplasms

,

,

diabetes mellitus

,

alzheimer disease

,

,

falciparum malaria

,

postmenopausal osteoporosis

,

,

prostatic hyperplasia

,

personal satisfaction

,

hypersensitivity

,

dentin sensitivity

,

tension-type headache

,

diabetic neuropathies

,

,

postoperative nausea and vomiting

,

,

,

,

,

respiratory sounds

,

allergic rhinitis seasonal

,

,

,

,

,

spinal cord injuries

,

,

erectile dysfunction

,

chronic obstructive pulmonary disease

,

,

,

type 2 diabetes mellitus

,

migraine disorders

,

obstructive lung diseases

,

communicable diseases

,

,

bipolar disorder

,

infectious skin diseases

,

insulin resistance

,

prostatic neoplasms

,

bacterial infections

,

bacterial skin diseases

,

,

,

soft tissue infections

,

,

,

,

healthy volunteers/patients

,

myeloid leukemia acute

,

myelodysplastic syndromes

,

chronic obstructive pulmonary disease

,

respiratory aspiration

,

congenital abnormalities

,

chromosome aberrations

,

colonic neoplasms

,

rectal neoplasms

,

neoplasm metastasis

,

myeloid leukemia

,

primary myelofibrosis

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

colorectal neoplasms

,

,

multiple myeloma

,

,

pancreatic neoplasms

,

sjogren's syndrome

,

,

amyotrophic lateral sclerosis

,

prostatic neoplasms

,

psychology rejection

,

ovarian neoplasms

,

thrombocytopenia

,

,

oligodendroglioma

,

,

hepatocellular carcinoma

,

liver neoplasms

,

chronic hepatitis c

,

chronic hepatitis

,

pancreatic ductal carcinoma

,

,

graft rejection

,

,

,

triple negative breast neoplasms

,

gastrointestinal neoplasms

,

gastrointestinal stromal tumors

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

neoplasm micrometastasis

,

uterine cervical neoplasms

,

,

meningococcal infections

,

,

,

motor neuron disease

,

hemolytic anemia autoimmune

,

castration-resistant prostatic neoplasms

,

x-linked bulbo-spinal atrophy

,

human influenza

,

breast neoplasms

,

chronic urticaria

,

,

,

haemophilus infections

,

liver transplantation

,

,

thrombocytopenic purpura idiopathic

,

,

,

,

chronic renal insufficiency

,

kidney diseases

,

,

psoriatic arthritis

,

,

influenza in birds

,

,

hematologic neoplasms

,

gouty arthritis

,

,

,

osteitis deformans

,

autoimmune hepatitis

,

juvenile arthritis

,

h5n1 subtype influenza a virus

,

,

hyperphosphatemia

,

,

communicable diseases

,

chronic hepatitis b

,

patient compliance

,

chronic disease

,

,

cryopyrin-associated periodic syndromes

,

,

lupus nephritis

,

systemic lupus erythematosus

,

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

neoplasms by site

,

kidney transplantation

,

,

,

,

,

tick-borne encephalitis

,

,

,

cystic fibrosis

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