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Company ReportsMirum Pharmaceuticals

Mirum Pharmaceuticals(MIRM)

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Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Livmarli	Maralixibat	2021-09-29	2031-2040	Pruritus , Alagille syndrome
Cholbam	Cholic acid	2015-03-17		Zellweger syndrome , Inborn errors metabolism

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

neurofibromatosis 1

,

,

hyperlipidemias

,

central nervous system neoplasms

,

neurofibromatoses

,

,

clostridium infections

,

colonic neoplasms

,

rectal neoplasms

,

,

hyperlipoproteinemia type iv

,

metabolic syndrome

,

hypertriglyceridemia

,

familial combined hyperlipidemia

,

liver function tests

,

,

alcoholic hepatitis

,

parkinson disease

,

huntington disease

,

cardiovascular diseases

,

,

,

alcoholic fatty liver

,

,

gastrointestinal diseases

,

digestive system diseases

,

liver neoplasms

,

,

rheumatoid arthritis

,

,

biliary tract diseases

,

barrett esophagus

,

reperfusion injury

,

,

cystic fibrosis

,

,

muscle spasticity

,

hereditary spastic paraplegia

,

,

irritable bowel syndrome

,

,

cardiomyopathies

,

disease progression

,

,

neoplasm metastasis

,

radiation injuries

,

,

insulin resistance

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

,

,

x-linked genetic diseases

,

smith-lemli-opitz syndrome

,

,

,

,

bile duct diseases

,

adolescent development

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

obstructive jaundice

,

,

esophageal neoplasms

,

head and neck neoplasms

,

end stage liver disease

,

,

,

breast neoplasms

,

acute kidney injury

,

kidney neoplasms

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

healthy volunteers/patients

,

intrahepatic cholestasis

,

colorectal neoplasms

,

cerebrotendinous xanthomatosis

,

,

,

,

pregnancy complications

,

glucose intolerance

,

sclerosing cholangitis

,

peroxisomal disorders

,

zellweger syndrome

,

infantile refsum disease

,

adrenoleukodystrophy

,

,

adenomatous polyposis coli

,

nasopharyngeal neoplasms

,

,

retinal detachment

,

dissociative disorders

,

chronic hepatitis c

,

duodenal neoplasms

,

inborn errors metabolism

,

inborn errors lipid metabolism

,

inborn errors steroid metabolism

,

,

follicular lymphoma

,

inborn genetic diseases

,

,

child nutrition disorders

,

ulcerative colitis

,

,

thyroid diseases

,

acute cholecystitis

,

,

acalculous cholecystitis

,

,

,

biliary liver cirrhosis

,

,

,

liver cirrhosis

,

non-alcoholic fatty liver disease

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

cholecystolithiasis

,

,

,

,

,

chemical and drug induced liver injury

,

,

gestational diabetes

,

,

autoimmune hepatitis

,

,

,

neonatal hyperbilirubinemia

,

malabsorption syndromes

,

lipid metabolism disorders

,

,

,

hemolytic anemia

,

chronic kidney failure

,

kidney diseases

,

short bowel syndrome

,

cardiac surgical procedures

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

fontan procedure

,

,

communicable diseases

,

,

brain neoplasms

,

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors

,

,

retinal neoplasms

,

neuroectodermal tumors

,

phenylketonurias

,

appetite regulation

,

,

liver transplantation

,

gastroesophageal reflux

,

,

biliary atresia

,

liver regeneration

,

hepatocellular carcinoma

,

cholangiocarcinoma

,

,

hyperbilirubinemia

,

,

glucosephosphate dehydrogenase deficiency

,

hepatic encephalopathy

,

transjugular intrahepatic portasystemic shunt

,

,

cerebrotendinous xanthomatosis

,

,

healthy volunteers/patients

,

,

biliary liver cirrhosis

,

substance withdrawal syndrome

,

biliary tract diseases

,

bile duct diseases

,

biliary atresia

,

digestive system diseases

,

sclerosing cholangitis

,

alagille syndrome

,

,

intrahepatic cholestasis

,

,

Maralixibat chloride

,

healthy volunteers/patients

,

,

biliary liver cirrhosis

,

biliary tract diseases

,

bile duct diseases

,

substance withdrawal syndrome

,

digestive system diseases

,

biliary atresia

,

sclerosing cholangitis

,

alagille syndrome

,

,

intrahepatic cholestasis

,

,

type 1 diabetes mellitus

,

,

,

,

type 2 diabetes mellitus

,

,

,

,

movement disorders

,

central nervous system diseases

,

,

neurodegenerative diseases

,

glucose metabolism disorders

,

metabolic diseases

,

endocrine system diseases

,

drug-induced akathisia

,

nervous system diseases

,

chronic hepatitis

,

parkinsonian disorders

,

drug-induced dyskinesia

,

postoperative pain

,

,

,

postherpetic neuralgia

,

liver cirrhosis

,

,

,

castration-resistant prostatic neoplasms

,

non-small-cell lung carcinoma

,

,

alzheimer disease

,

,

thyroid neoplasms

,

thyroid diseases

,

parkinson disease

,

diabetes mellitus

,

chronic hepatitis c

,

,

acquired immunodeficiency syndrome

,

,

immunologic deficiency syndromes

,

small cell lung carcinoma

,

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

,

rheumatoid arthritis

,

,

neuromuscular blockade

,

prostatic neoplasms

,

,

,

chronic renal insufficiency

,

acute coronary syndrome

,

kidney diseases

,

,

,

,

uterine prolapse

,

intestinal obstruction

,

,

spinal diseases

,

delayed emergence from anesthesia

,

,

,

muscle relaxation

,

,

,

,

urinary retention

,

,

female infertility

,

uterine diseases

,

postoperative complications

,

,

wound infection

,

surgical wound infection

multiple myeloma

,

b-cell chronic lymphocytic leukemia

,

plasma cell neoplasms

,

hodgkin disease

,

,

breast neoplasms

,

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

,

pregnancy complications

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

,

digestive system diseases

,

healthy volunteers/patients

,

colorectal neoplasms

,

chronic renal insufficiency

,

kidney diseases

,

sickle cell anemia

,

knee osteoarthritis

,

,

,

,

ovarian neoplasms

,

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

laryngeal neoplasms

,

opioid-related disorders

,

,

coronavirus infections

,

,

,

brain neoplasms

,

,

neurofibromatosis 2

,

acoustic neuroma

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

cystic fibrosis

,

,

soft tissue neoplasms

,

biliary tract neoplasms

,

,

urinary bladder neoplasms

,

invasive hydatidiform mole

,

non-muscle invasive bladder neoplasms

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

b-cell lymphoma

,

b-cell leukemia

,

diabetes mellitus

,

chronic obstructive pulmonary disease

,

,

non-small-cell lung carcinoma

,

,

pulmonary eosinophilia

,

,

,

,

,

endometrial neoplasms

,

borderline personality disorder

,

personality disorders

,

churg-strauss syndrome

,

eosinophilic granuloma

,

type 2 diabetes mellitus

,

breast neoplasms

,

,

,

,

endomyocardial fibrosis

,

postoperative pain

,

,

major depressive disorder

,

depressive disorder

,

systemic lupus erythematosus

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

,

pregnancy complications

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

,

digestive system diseases

,

Histone-arginine methyltransferase carm1

pharmacokinetics

,

chronic obstructive pulmonary disease

,

respiratory aspiration

,

positron-emission tomography

,

,

alzheimer disease

,

diagnostic imaging

,

medical sociology

,

drug interactions

,

electrocardiography

,

therapeutic equivalency

,

neuroinflammatory diseases

,

pharmacological phenomena

,

,

,

stomach neoplasms

,

hypophosphatemia

,

hematologic neoplasms

,

cystic fibrosis

,

pseudomonas infections

,

biological availability

,

castration-resistant prostatic neoplasms

,

,

non-small-cell lung carcinoma

,

breast neoplasms

,

postcoital contraception

,

ovulation inhibition

,

atrial fibrillation

,

,

,

parkinson disease

,

small cell lung carcinoma

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

cardiomyopathies

,

,

,

,

overactive urinary bladder

,

hormonal contraception

,

unplanned pregnancy

,

b-cell lymphoma

,

,

skin abnormalities

,

myocardial infarction

,

,

acquired immunodeficiency syndrome

,

magnetic resonance angiography

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

coronary disease

,

myocardial ischemia

,

interstitial lung diseases

,

thyroid neoplasms

,

thyroid diseases

,

pancreatic neoplasms

,

,

,

,

,

prostatic hyperplasia

,

,

angina pectoris

,

,

ischemic stroke

,

,

cerebral infarction

,

urologic neoplasms

,

head and neck neoplasms

,

thromboembolism

,

venous thromboembolism

,

pulmonary hypertension

,

hyperphosphatemia

,

chronic renal insufficiency

,

multiple sclerosis

,

non-hodgkin lymphoma

,

,

prostatic neoplasms

,

surgical blood loss

,

venous thrombosis

,

,

essential hypertension

,

kidney diseases

,

,

,

,

,

peripheral vascular diseases

,

postoperative hemorrhage

,

pulmonary embolism

,

cardiovascular diseases

,

,

spinal cord injuries

,

peripheral arterial disease

,

renal artery obstruction

,

,

bacterial infections

,

,

,

,

intraabdominal infections

,

,

chronic progressive multiple sclerosis

,

blood coagulation disorders

,

hormone replacement therapy

,

hyperlipidemias

,

hyperlipoproteinemias

,

choroidal neovascularization

,

,

degenerative myopia

,

pathologic neovascularization

,

,

aspiration pneumonia

,

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

metabolic bone diseases

,

premenstrual dysphoric disorder

,

diabetic nephropathies

,

,

follicular lymphoma

,

wounds and injuries

,

brain neoplasms

,

cardiovascular abnormalities

,

pathologic constriction

,

,

vascular diseases

,

memory disorders

,

carotid stenosis

,

pulmonary arterial hypertension

,

,

,

depressive disorder

,

aortic valve stenosis

,

heart valve diseases

,

ventricular outflow obstruction

,

,

abdominal abscess

,

erectile dysfunction

,

,

,

,

,

,

healthy volunteers/patients

,

renal cell carcinoma

,

,

,

atopic dermatitis

,

liver neoplasms

,

,

,

communicable diseases

,

relapsing-remitting multiple sclerosis

,

,

,

hepatocellular carcinoma

,

urinary tract infections

,

diabetes mellitus

,

coronary artery disease

,

,

type 2 diabetes mellitus

,

colorectal neoplasms

,

,

,

,

physiological sexual dysfunction

,

magnetic resonance imaging

,

neoplasm metastasis

,

acute coronary syndrome

,

tension-type headache

,

,

,

peripheral nervous system diseases

,

renal insufficiency

,

chronic bronchitis

,

,

,

,

,

respiratory tract infections

,

,

ischemic optic neuropathy

,

optic nerve diseases

,

,

,

macular degeneration

,

energy metabolism

,

,

maxillary sinusitis

,

community-acquired pneumonia

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

medicated intrauterine devices

,

,

gene expression

,

cell proliferation

,

,

,

central nervous system neoplasms

,

photoallergic dermatitis

,

phototoxic dermatitis

,

four-dimensional computed tomography

healthy volunteers/patients

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

biphenotypic leukemia acute

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia acute

,

monocytic leukemia acute

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

burkitt lymphoma

,

,

parkinson disease

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