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Company ReportsMirum Pharmaceuticals

Mirum Pharmaceuticals(MIRM)

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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Livmarli	Maralixibat	2021-09-29	2031-2040	Pruritus , Alagille syndrome
Cholbam	Cholic acid	2015-03-17		Zellweger syndrome , Inborn errors metabolism

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

inborn errors steroid metabolism

,

,

peroxisomal disorders

,

zellweger syndrome

,

infantile refsum disease

,

adrenoleukodystrophy

,

,

healthy volunteers/patients

,

substance withdrawal syndrome

,

biliary atresia

,

,

,

alagille syndrome

,

,

intrahepatic cholestasis

,

,

,

cystic fibrosis

,

Maralixibat chloride

,

healthy volunteers/patients

,

,

alagille syndrome

,

liver cirrhosis

,

,

biliary liver cirrhosis

,

substance withdrawal syndrome

,

biliary atresia

,

sclerosing cholangitis

,

,

,

,

intrahepatic cholestasis

,

large b-cell lymphoma diffuse

,

multiple myeloma

,

b-cell chronic lymphocytic leukemia

,

follicular lymphoma

,

,

,

,

hodgkin disease

,

mantle-cell lymphoma

,

b-cell lymphoma

,

triple negative breast neoplasms

,

renal cell carcinoma

,

,

,

,

chronic hepatitis b

,

communicable diseases

,

,

parkinson disease

,

parkinsonian disorders

,

movement disorders

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

chronic renal insufficiency

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

graft vs host disease

,

type 1 diabetes mellitus

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

brain neoplasms

,

,

oligodendroglioma

,

pancreatic neoplasms

,

,

neuroendocrine tumors

,

islet cell carcinoma

,

,

,

somatostatinoma

,

,

,

breast neoplasms

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

,

,

retinal vein occlusion

,

vision disorders

,

,

macular degeneration

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

juvenile arthritis

,

,

kidney diseases

,

myocardial infarction

,

,

inferior wall myocardial infarction

,

organ transplantation

,

wet macular degeneration

,

neoplasm metastasis

,

graft rejection

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

,

non-alcoholic fatty liver disease

,

,

postoperative pain

,

,

choroidal neovascularization

,

pathologic neovascularization

,

chronic kidney failure

,

renal insufficiency

,

liver transplantation

,

kidney transplantation

,

,

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

liver cirrhosis

,

,

atrial fibrillation

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

pregnancy complications

,

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

Sodium chloride

,

,

,

,

,

,

depressive disorder

,

,

streptococcal infections

,

streptococcus agalactiae

,

,

acute kidney injury

,

wounds and injuries

,

,

,

aplastic anemia

,

,

hematologic neoplasms

,

,

cutaneous malignant melanoma

,

major depressive disorder

,

suicidal ideation

,

stomach neoplasms

,

bacterial infections

,

gram-positive bacterial infections

,

diabetic nephropathies

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

parkinson disease

,

healthy volunteers/patients

,

peritoneal neoplasms

,

intestinal obstruction

,

triple negative breast neoplasms

,

complex regional pain syndromes

,

reflex sympathetic dystrophy

,

somatoform disorders

,

,

,

congenital hyperinsulinism

,

nesidioblastosis

,

hyperinsulinism

,

,

eosinophilic esophagitis

,

,

sickle cell anemia

,

treatment-resistant depressive disorder

,

meningococcal infections

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

,

,

non-small-cell lung carcinoma

,

,

homozygous familial hypercholesterolemia

,

,

meningococcal meningitis

,

cardiovascular diseases

,

,

kidney diseases

,

renal cell carcinoma

,

,

cystic fibrosis

,

prostatic neoplasms

,

,

,

pancreatic neoplasms

,

chronic renal insufficiency

,

kidney transplantation

,

graft rejection

,

,

,

,

,

japanese encephalitis

,

respiratory tract infections

,

,

,

metabolic bone diseases

,

,

,

pulmonary eosinophilia

,

hepatocellular carcinoma

,

liver neoplasms

,

gastrointestinal stromal tumors

,

atherosclerosis

,

,

,

diabetes complications

,

vitreous hemorrhage

,

,

essential hypertension

,

metabolic syndrome

,

,

,

systolic murmurs

,

isolated systolic hypertension

,

neoplasm metastasis

,

,

human influenza

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

breast neoplasms

,

hypersensitivity

,

left ventricular hypertrophy

,

,

,

,

communicable diseases

,

,

diabetic retinopathy

,

,

insulin resistance

,

prehypertension

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

type 2 diabetes mellitus

,

,

,

retinal diseases

,

hip osteoarthritis

,

,

food hypersensitivity

,

abdominal obesity

,

retinal neovascularization

,

pathologic neovascularization

,

migraine disorders

,

migraine without aura

,

angina pectoris

,

microvascular angina

,

,

migraine with aura

,

health risk behaviors

,

vascular stiffness

hyperlipidemias

,

gastrointestinal stromal tumors

,

,

iron-deficiency anemia

,

iron deficiencies

,

,

,

,

small cell lung carcinoma

,

healthy volunteers/patients

,

,

primary myelofibrosis

,

myeloid leukemia acute

,

myeloid leukemia

,

,

hepatocellular carcinoma

,

,

plexiform neurofibroma

,

neurofibromatoses

,

,

,

,

chronic obstructive pulmonary disease

,

,

triple negative breast neoplasms

,

,

,

essential thrombocythemia

,

polycythemia vera

,

,

,

lupus nephritis

,

,

inflammatory breast neoplasms

,

prostatic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

wiskott-aldrich syndrome

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

hyperlipoproteinemia type ii

,

organ transplantation

,

homozygous familial hypercholesterolemia

,

cryopyrin-associated periodic syndromes

,

myelodysplastic syndromes

,

,

liver transplantation

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

parkinson disease

,

,

,

juvenile arthritis

,

,

,

,

hepatitis b virus

,

,

,

,

vision disorders

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

,

acute coronary syndrome

,

,

,

pulmonary eosinophilia

,

pancreatic neoplasms

,

,

,

kidney transplantation

,

,

hypercholesterolemia

,

cardiovascular diseases

,

atherosclerosis

,

chronic kidney failure

,

kidney diseases

,

thrombocytopenia

,

,

breast neoplasms

,

,

renal insufficiency

,

,

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

heart transplantation

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

,

cystic fibrosis

,

pseudomonas infections

,

type 2 diabetes mellitus

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

transplantation

,

cytomegalovirus infections

,

communicable diseases

,

,

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

pregnancy complications

,

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

myeloid leukemia acute

,

myeloid leukemia

,

healthy volunteers/patients

,

myelodysplastic syndromes

,

,

renal cell carcinoma

,

streptococcal infections

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

,

sjogren's syndrome

,

pancreatic ductal carcinoma

,

,

multiple myeloma

,

primary myelofibrosis

,

,

pancreatic neoplasms

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

triple negative breast neoplasms

,

ovarian neoplasms

,

plasma cell neoplasms

,

,

,

,

oligodendroglioma

,

,

chronic hepatitis c

,

chronic hepatitis

,

,

graft rejection

,

,

falciparum malaria

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

hematologic neoplasms

,

meningococcal infections

,

ovarian epithelial carcinoma

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

colonic neoplasms

,

neoplasm micrometastasis

,

uterine cervical neoplasms

,

rheumatoid arthritis

,

autoimmune diseases

,

systemic lupus erythematosus

,

breast neoplasms

,

chronic urticaria

,

,

,

,

,

,

haemophilus infections

,

liver transplantation

,

,

,

chronic renal insufficiency

,

kidney diseases

,

psoriatic arthritis

,

,

,

influenza in birds

,

chronic disease

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

gouty arthritis

,

,

,

autoimmune hepatitis

,

juvenile arthritis

,

,

haemophilus influenzae

,

hyperphosphatemia

,

chronic hepatitis b

,

,

cryopyrin-associated periodic syndromes

,

,

lupus nephritis

,

,

vascular diseases

,

polypoidal choroidal vasculopathy

,

h5n1 subtype influenza a virus

,

,

human influenza

,

kidney transplantation

,

,

,

,

,

,

tick-borne encephalitis

,

,

communicable diseases

,

cystic fibrosis

,

h1n1 subtype influenza a virus

,

cytomegalovirus infections

,

,

healthy volunteers/patients

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

congenital abnormalities

,

chromosome aberrations

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

multiple myeloma

,

,

pancreatic neoplasms

,

primary myelofibrosis

,

sjogren's syndrome

,

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

plasma cell neoplasms

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

,

oligodendroglioma

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

chronic hepatitis c

,

chronic hepatitis

,

pancreatic ductal carcinoma

,

,

,

graft rejection

,

,

falciparum malaria

,

,

triple negative breast neoplasms

,

gastrointestinal neoplasms

,

gastrointestinal stromal tumors

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

neoplasm micrometastasis

,

uterine cervical neoplasms

,

,

hematologic neoplasms

,

meningococcal infections

,

,

,

human influenza

,

breast neoplasms

,

chronic urticaria

,

,

,

,

,

haemophilus infections

,

liver transplantation

,

,

,

chronic renal insufficiency

,

kidney diseases

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

psoriatic arthritis

,

,

influenza in birds

,

,

gouty arthritis

,

,

,

autoimmune hepatitis

,

juvenile arthritis

,

h5n1 subtype influenza a virus

,

,

hyperphosphatemia

,

,

communicable diseases

,

,

chronic hepatitis b

,

chronic disease

,

,

cryopyrin-associated periodic syndromes

,

,

lupus nephritis

,

,

,

,

kidney transplantation

,

,

,

tick-borne encephalitis

,

,

,

cystic fibrosis

healthy volunteers/patients

,

,

,

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma

,

lymphoid leukemia

,

,

,

,

,

respiratory aspiration

,

breast neoplasms

,

,

ankylosing spondylitis

,

spondylarthritis

,

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